TOP CONOLIDINE ALKALOID FOR CHRONIC PAIN SECRETS

Most lately, it's been identified that conolidine and the above derivatives act to the atypical chemokine receptor three (ACKR3. Expressed in comparable spots as classical opioid receptors, it binds to the wide array of endogenous opioids. In contrast to most opioid receptors, this receptor acts like a scavenger and will not activate a 2nd messenge